MiCBT Research (Selected Studies)

Research and Publications on Mindfulness-integrated CBT.

Effects of Mindfulness-integrated CBT on selective attention and frontal lobe EEG asymmetry in patients with multiple sclerosis and healthy controls

Monday, December 16, 2019

Fazilat-Pour, M.1, Atefeh, F.1, Cayoun, B. A.2*

1 Faculty of Education and Psychology, Shiraz University, Shiraz, Iran
2 MiCBT Institute, Hobart, Tasmania 7000, Australia


Background: Frontal lobe EEG asymmetry has been shown to predict one’s tendencies towards approach versus avoidance and related affective states. This study examines the effects of Mindfulness-integrated Cognitive Behavior Therapy (MiCBT) on selective attention and related executive functions and on frontal lobe EEG asymmetry in 24 adults with multiple sclerosis (MS) referred to the Kerman Multiple Sclerosis charity and 20 healthy controls.

Method: Participants were recruited using a convenience sampling method. Both MS and control participants were each randomly allocated to two groups, forming two (MiCBT) intervention groups (nMS=14), nhealthy=14) and two control groups (nMS=10, nhealthy=10). All participants completed the classic version of the Stroop task followed by an assessment of frontal EEG asymmetry before and after the intervention.

Results: The results showed that selective attention and frontal lobe frequency EEG increased in the MiCBT groups but not in the control groups. In addition, the MS and healthy participants in the MiCBT groups displayed increased frequency in the beta band (13-30 Hz) on the left frontal lobe, suggesting increased positive emotions in these groups; this effect did not occur in the control groups.

Discussion: Although replication studies are needed, these early findings indicate that MiCBT may be an intervention that improves selective attention and positive emotions in people with MS and healthy individuals in the general community.

(Manuscript in preparation)
*Corresponding author

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